TL;DR: (R)-ranolazine (CAS 1054624-77-9) is a chemical compound with molecular formula C24H33N3O4 and molecular weight 427.2471 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(2,6-dimethylphenyl)-2-[4-[(2R)-2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
Also Known As: (R)-ranolazine, Ranexa, Ranolazine-d3, Lopac-R-6152, N-(2,6-dimethylphenyl)-2-[4-[(2R)-2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
| Molecular Formula | C24H33N3O4 |
| Molecular Weight | 427.2471 g/mol |
| XLogP | 2.7 |
| Topological Polar Surface Area (TPSA) | 74.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Exact Mass | 427.2471 Da |
| Heavy Atoms | 31 |
| Complexity | 531.0 |
| SMILES | CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)C[C@H](COC3=CC=CC=C3OC)O |
| InChIKey | XKLMZUWKNUAPSZ-HXUWFJFHSA-N |
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (R)-ranolazine. The TPSA of 74.3 Ų falls within the moderate polarity range, balancing permeability and solubility for (R)-ranolazine. Following Lipinski's Rule of Five, (R)-ranolazine has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of (R)-ranolazine is 1054624-77-9.
The molecular formula of (R)-ranolazine is C24H33N3O4.
The molecular weight of (R)-ranolazine is 427.2471 g/mol.
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