5-Fluoromethyl MK 801
TL;DR: 5-Fluoromethyl MK 801 (CAS 119493-73-1) is a chemical compound with molecular formula C17H16FN and molecular weight 252.12921 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(2-(18F)fluoroethyl)-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2,4,6,10,12,14-hexaene
Also Known As: 5-Fluoromethyl MK 801, 5-Fluoromethyldizocilpine, 5-FM-MK 801, 5-[2-(~18~F)Fluoroethyl]-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, 1-(2-(18F)fluoranylethyl)-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2,4,6,10,12,14-hexaene
Technical Specifications
| Molecular Formula | C17H16FN |
| Molecular Weight | 252.12921 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 12.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 252.12921 Da |
| Heavy Atoms | 19 |
| Complexity | 344.0 |
| SMILES | C1C2C3=CC=CC=C3C(N2)(C4=CC=CC=C41)CC[18F] |
| InChIKey | DHHVHCZZAHJZSA-SQZVAGKESA-N |
Chemical Property Profile of 5-Fluoromethyl MK 801
Property Insights of 5-Fluoromethyl MK 801
The XLogP value of 3.2 indicates that 5-Fluoromethyl MK 801 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.0 Ų, 5-Fluoromethyl MK 801 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Fluoromethyl MK 801 has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Fluoromethyl MK 801?
The CAS number of 5-Fluoromethyl MK 801 is 119493-73-1.
What is the molecular formula of 5-Fluoromethyl MK 801?
The molecular formula of 5-Fluoromethyl MK 801 is C17H16FN.
What is the molecular weight of 5-Fluoromethyl MK 801?
The molecular weight of 5-Fluoromethyl MK 801 is 252.12921 g/mol.
Where can I buy 5-Fluoromethyl MK 801?
You can request a quote for 5-Fluoromethyl MK 801 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Fluoromethyl MK 801?
Yes, CoreyChem provides custom synthesis services for 5-Fluoromethyl MK 801 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.