L-657,743 hydrochloride
TL;DR: L-657,743 hydrochloride (CAS 119942-70-0) is a chemical compound with molecular formula C20H26ClN3O2 and molecular weight 375.17136 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1',3'-dimethylspiro[1,3,4,6,7,12b-hexahydro-[1]benzofuro[2,3-a]quinolizine-2,4'-1,3-diazinane]-2'-one;hydrochloride
Also Known As: MK-912 hydrate, L-657,743 hydrochloride, Tox21_500760, MK 912, MK 0912
Technical Specifications
| Molecular Formula | C20H26ClN3O2 |
| Molecular Weight | 375.17136 g/mol |
| XLogP | 3.6737 |
| Topological Polar Surface Area (TPSA) | 39.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 375.17136 Da |
| Heavy Atoms | 26 |
| Complexity | 555.0 |
| SMILES | CN1CCC2(CCN3CCC4=C(C3C2)OC5=CC=CC=C45)N(C1=O)C.Cl |
| InChIKey | ALYCEQJIRFYVGE-UHFFFAOYSA-N |
Chemical Property Profile of L-657,743 hydrochloride
Property Insights of L-657,743 hydrochloride
The XLogP value of 3.6737 indicates that L-657,743 hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 39.9 Ų, L-657,743 hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, L-657,743 hydrochloride has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of L-657,743 hydrochloride?
The CAS number of L-657,743 hydrochloride is 119942-70-0.
What is the molecular formula of L-657,743 hydrochloride?
The molecular formula of L-657,743 hydrochloride is C20H26ClN3O2.
What is the molecular weight of L-657,743 hydrochloride?
The molecular weight of L-657,743 hydrochloride is 375.17136 g/mol.
Where can I buy L-657,743 hydrochloride?
You can request a quote for L-657,743 hydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for L-657,743 hydrochloride?
Yes, CoreyChem provides custom synthesis services for L-657,743 hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.