Naftopidil, (R)-
TL;DR: Naftopidil, (R)- (CAS 127931-15-1) is a chemical compound with molecular formula C24H28N2O3 and molecular weight 392.21 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol
Also Known As: naftopidil, (-)-Naftopidil, Naftopidil, (R)-, R-(-)-Naftopidil, (R)-naftopidil
Technical Specifications
| Molecular Formula | C24H28N2O3 |
| Molecular Weight | 392.21 g/mol |
| XLogP | 4.1 |
| Topological Polar Surface Area (TPSA) | 45.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 392.21 Da |
| Heavy Atoms | 29 |
| Complexity | 483.0 |
| SMILES | COC1=CC=CC=C1N2CCN(CC2)C[C@H](COC3=CC=CC4=CC=CC=C43)O |
| InChIKey | HRRBJVNMSRJFHQ-HXUWFJFHSA-N |
Chemical Property Profile of Naftopidil, (R)-
Property Insights of Naftopidil, (R)-
The XLogP value of 4.1 indicates that Naftopidil, (R)- is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.2 Ų, Naftopidil, (R)- exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Naftopidil, (R)- has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Naftopidil, (R)-?
The CAS number of Naftopidil, (R)- is 127931-15-1.
What is the molecular formula of Naftopidil, (R)-?
The molecular formula of Naftopidil, (R)- is C24H28N2O3.
What is the molecular weight of Naftopidil, (R)-?
The molecular weight of Naftopidil, (R)- is 392.21 g/mol.
Where can I buy Naftopidil, (R)-?
You can request a quote for Naftopidil, (R)- directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Naftopidil, (R)-?
Yes, CoreyChem provides custom synthesis services for Naftopidil, (R)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.