![1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine structure](/static/products/281/2814486-79-6.webp)
1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine
TL;DR: 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine (CAS 2814486-79-6) is a chemical compound with molecular formula C13H14FN3S and molecular weight 263.08923 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-(4-fluorophenyl)-2-piperazin-1-yl-1,3-thiazole
Also Known As: DYRK1A inhibitor compound 11, 1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine, 1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]piperazine trihydrate, 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine, 4-(4-fluorophenyl)-2-piperazin-1-yl-1,3-thiazole
Technical Specifications
| Molecular Formula | C13H14FN3S |
| Molecular Weight | 263.08923 g/mol |
| XLogP | 2.5 |
| Topological Polar Surface Area (TPSA) | 56.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 263.08923 Da |
| Heavy Atoms | 18 |
| Complexity | 265.0 |
| SMILES | C1CN(CCN1)C2=NC(=CS2)C3=CC=C(C=C3)F |
| InChIKey | DZOSNUNUESTDRS-UHFFFAOYSA-N |
Chemical Property Profile of 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine
Property Insights of 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine. With a topological polar surface area (TPSA) of 56.4 Ų, 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine?
The CAS number of 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine is 2814486-79-6.
What is the molecular formula of 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine?
The molecular formula of 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine is C13H14FN3S.
What is the molecular weight of 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine?
The molecular weight of 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine is 263.08923 g/mol.
Where can I buy 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine?
You can request a quote for 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine?
Yes, CoreyChem provides custom synthesis services for 1-[4-(4-Fluorophenyl)-2-thiazolyl]piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.