4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one
TL;DR: 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one (CAS 309721-29-7) is a chemical compound with molecular formula C24H18FNO3 and molecular weight 387.12708 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(4E)-5-(2-fluorophenyl)-4-[hydroxy(phenyl)methylidene]-1-(3-methylphenyl)pyrrolidine-2,3-dione
Also Known As: 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one, (4E)-5-(2-fluorophenyl)-4-[hydroxy(phenyl)methylidene]-1-(3-methylphenyl)pyrrolidine-2,3-dione, 4-Benzoyl-5-(2-fluoro-phenyl)-3-hydroxy-1-m-tolyl-1,5-dihydro-pyrrol-2-one, 4-Benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(3-methylphenyl)-1,5-dihydro-2H-pyrrol-2-one #, 4-BENZOYL-5-(2-FLUOROPHENYL)-3-HYDROXY-1-(3-METHYLPHENYL)-2,5-DIHYDRO-1H-PYRROL-2-ONE
Technical Specifications
| Molecular Formula | C24H18FNO3 |
| Molecular Weight | 387.12708 g/mol |
| XLogP | 5.0 |
| Topological Polar Surface Area (TPSA) | 57.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 387.12708 Da |
| Heavy Atoms | 29 |
| Complexity | 669.0 |
| SMILES | CC1=CC(=CC=C1)N2C(/C(=C(/C3=CC=CC=C3)\O)/C(=O)C2=O)C4=CC=CC=C4F |
| InChIKey | ZFMLLOQIIQSNPX-LSDHQDQOSA-N |
Chemical Property Profile of 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one
Property Insights of 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one
The XLogP value of 5.0 indicates that 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.6 Ų, 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one?
The CAS number of 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one is 309721-29-7.
What is the molecular formula of 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one?
The molecular formula of 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one is C24H18FNO3.
What is the molecular weight of 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one?
The molecular weight of 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one is 387.12708 g/mol.
Where can I buy 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one?
You can request a quote for 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one?
Yes, CoreyChem provides custom synthesis services for 4-benzoyl-5-(2-fluorophenyl)-3-hydroxy-1-(m-tolyl)-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.