1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide
TL;DR: 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide (CAS 337504-67-3) is a chemical compound with molecular formula C23H21FN6O4S and molecular weight 496.1329 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-ethyl-6-fluoro-7-[4-(furan-2-carbonyl)piperazin-1-yl]-4-oxo-N-(1,3,4-thiadiazol-2-yl)quinoline-3-carboxamide
Also Known As: 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide, 1-ethyl-6-fluoro-7-[4-(2-furoyl)-1-piperazinyl]-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydro-3-quinolinecarboxamide, 1-ethyl-6-fluoro-7-[4-(furan-2-carbonyl)piperazin-1-yl]-4-oxo-N-(1,3,4-thiadiazol-2-yl)quinoline-3-carboxamide, 1-ethyl-6-fluoro-7-[4-(furan-2-ylcarbonyl)piperazin-1-yl]-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide
Technical Specifications
| Molecular Formula | C23H21FN6O4S |
| Molecular Weight | 496.1329 g/mol |
| XLogP | 2.4 |
| Topological Polar Surface Area (TPSA) | 140.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 5 |
| Exact Mass | 496.1329 Da |
| Heavy Atoms | 35 |
| Complexity | 869.0 |
| SMILES | CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C(=O)C4=CC=CO4)F)C(=O)NC5=NN=CS5 |
| InChIKey | BYWZJBFPWYSTGX-UHFFFAOYSA-N |
Chemical Property Profile of 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide
Property Insights of 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide
The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide. The TPSA of 140.0 Ų indicates high polarity, suggesting 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide has 1 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide?
The CAS number of 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide is 337504-67-3.
What is the molecular formula of 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide?
The molecular formula of 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide is C23H21FN6O4S.
What is the molecular weight of 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide?
The molecular weight of 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide is 496.1329 g/mol.
Where can I buy 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide?
You can request a quote for 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide?
Yes, CoreyChem provides custom synthesis services for 1-ethyl-6-fluoro-7-(4-(furan-2-carbonyl)piperazin-1-yl)-4-oxo-N-(1,3,4-thiadiazol-2-yl)-1,4-dihydroquinoline-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.