(E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide
TL;DR: (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide (CAS 341988-53-2) is a chemical compound with molecular formula C12H10ClN3OS and molecular weight 279.02332 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-6-methylpyridine-3-carboxamide
Also Known As: (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide, N-[(E)-(5-chlorothiophen-2-yl)methylideneamino]-6-methylpyridine-3-carboxamide
Technical Specifications
| Molecular Formula | C12H10ClN3OS |
| Molecular Weight | 279.02332 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 82.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 279.02332 Da |
| Heavy Atoms | 18 |
| Complexity | 326.0 |
| SMILES | CC1=NC=C(C=C1)C(=O)N/N=C/C2=CC=C(S2)Cl |
| InChIKey | XPMCZCVYTNULSU-VIZOYTHASA-N |
Chemical Property Profile of (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide
Property Insights of (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide
The XLogP value of 3.1 indicates that (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 82.6 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide. Following Lipinski's Rule of Five, (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide?
The CAS number of (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide is 341988-53-2.
What is the molecular formula of (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide?
The molecular formula of (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide is C12H10ClN3OS.
What is the molecular weight of (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide?
The molecular weight of (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide is 279.02332 g/mol.
Where can I buy (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide?
You can request a quote for (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide?
Yes, CoreyChem provides custom synthesis services for (E)-N'-((5-chlorothiophen-2-yl)methylene)-6-methylnicotinohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.