TL;DR: (Z)-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-2-phenoxyacetamide (CAS 364051-73-0) is a chemical compound with molecular formula C18H16N4O4 and molecular weight 352.11716 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[(2-hydroxy-1H-indol-3-yl)imino]-2-[(2-phenoxyacetyl)amino]acetamide
Also Known As: N-[2-oxo-2-[2-(2-oxoindol-3-yl)hydrazinyl]ethyl]-2-phenoxyacetamide, (Z)-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-2-phenoxyacetamide, N-({N'-[(3Z)-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YLIDENE]HYDRAZINECARBONYL}METHYL)-2-PHENOXYACETAMIDE, N-{2-oxo-2-[(2Z)-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinyl]ethyl}-2-phenoxyacetamide (non-preferred name)
| Molecular Formula | C18H16N4O4 |
| Molecular Weight | 352.11716 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 116.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 352.11716 Da |
| Heavy Atoms | 26 |
| Complexity | 521.0 |
| SMILES | C1=CC=C(C=C1)OCC(=O)NCC(=O)N=NC2=C(NC3=CC=CC=C32)O |
| InChIKey | GQPCZXIPAFKFAU-UHFFFAOYSA-N |
The XLogP value of 3.1 indicates that (Z)-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-2-phenoxyacetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 116.0 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-2-phenoxyacetamide. Following Lipinski's Rule of Five, (Z)-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-2-phenoxyacetamide has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of (Z)-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-2-phenoxyacetamide is 364051-73-0.
The molecular formula of (Z)-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-2-phenoxyacetamide is C18H16N4O4.
The molecular weight of (Z)-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-2-phenoxyacetamide is 352.11716 g/mol.
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