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N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide structure
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N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide

TL;DR: N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide (CAS 365429-11-4) is a chemical compound with molecular formula C20H21N3OS and molecular weight 351.14053 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.

N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridinyl]propanamide

Also Known As: N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide, N-[4-(2-Ethyl-4-m-tolyl-thiazol-5-yl)-pyridin-2-yl]-propionamide, N-[4-[2-ETHYL-4-(3-METHYLPHENYL)-1,3-THIAZOL-5-YL]-2-PYRIDYL]PROPIONAMIDE, N-{4-[2-ETHYL-4-(3-METHYLPHENYL)-1,3-THIAZOL-5-YL]PYRIDIN-2-YL}PROPANAMIDE

CAS Number
365429-11-4
Molecular Formula
C20H21N3OS
Molecular Weight
351.14053 g/mol
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Technical Specifications

Molecular FormulaC20H21N3OS
Molecular Weight351.14053 g/mol
XLogP4.4
Topological Polar Surface Area (TPSA)83.1 Ų
Hydrogen Bond Donors1
Hydrogen Bond Acceptors4
Rotatable Bonds5
Exact Mass351.14053 Da
Heavy Atoms25
Complexity447.0
SMILESCCC1=NC(=C(S1)C2=CC(=NC=C2)NC(=O)CC)C3=CC=CC(=C3)C
InChIKeyQVEWLQUEUPMWAW-UHFFFAOYSA-N

Chemical Property Profile of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide

XLogP
4.4
TPSA (Topological Polar Surface Area)
83.1
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
5
Heavy Atoms
25
Complexity
447.0
Exact Mass
351.14053
Monoisotopic Mass
351.14053
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide

The XLogP value of 4.4 indicates that N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.1 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide. Following Lipinski's Rule of Five, N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the CAS number of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide?

The CAS number of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide is 365429-11-4.

What is the molecular formula of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide?

The molecular formula of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide is C20H21N3OS.

What is the molecular weight of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide?

The molecular weight of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide is 351.14053 g/mol.

Where can I buy N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide?

You can request a quote for N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.

Does CoreyChem offer custom synthesis for N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide?

Yes, CoreyChem provides custom synthesis services for N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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