F1222-0373
TL;DR: F1222-0373 (CAS 418797-78-1) is a chemical compound with molecular formula C18H15ClFN3OS and molecular weight 375.06085 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-(3-chlorophenyl)-N-(4-fluorophenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
Also Known As: F1222-0373, 4-(3-chlorophenyl)-N-(4-fluorophenyl)-6-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxamide, 4-(3-chlorophenyl)-N-(4-fluorophenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide, 4-(3-chlorophenyl)-N-(4-fluorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
Technical Specifications
| Molecular Formula | C18H15ClFN3OS |
| Molecular Weight | 375.06085 g/mol |
| XLogP | 3.3 |
| Topological Polar Surface Area (TPSA) | 85.3 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 375.06085 Da |
| Heavy Atoms | 25 |
| Complexity | 563.0 |
| SMILES | CC1=C(C(NC(=S)N1)C2=CC(=CC=C2)Cl)C(=O)NC3=CC=C(C=C3)F |
| InChIKey | TXGRWCUSZRIRGI-UHFFFAOYSA-N |
Chemical Property Profile of F1222-0373
Property Insights of F1222-0373
The XLogP value of 3.3 indicates that F1222-0373 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.3 Ų falls within the moderate polarity range, balancing permeability and solubility for F1222-0373. Following Lipinski's Rule of Five, F1222-0373 has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of F1222-0373?
The CAS number of F1222-0373 is 418797-78-1.
What is the molecular formula of F1222-0373?
The molecular formula of F1222-0373 is C18H15ClFN3OS.
What is the molecular weight of F1222-0373?
The molecular weight of F1222-0373 is 375.06085 g/mol.
Where can I buy F1222-0373?
You can request a quote for F1222-0373 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for F1222-0373?
Yes, CoreyChem provides custom synthesis services for F1222-0373 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.