Avanafil
TL;DR: Avanafil (CAS 647841-09-6) is a chemical compound with molecular formula C23H26ClN7O3 and molecular weight 483.17856 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Also Known As: Avanafil, Spedra, STENDRA, Avanafilo, avanafilum
Technical Specifications
| Molecular Formula | C23H26ClN7O3 |
| Molecular Weight | 483.17856 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 125.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 9 |
| Exact Mass | 483.17856 Da |
| Heavy Atoms | 34 |
| Complexity | 642.0 |
| SMILES | COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCC[C@H]4CO)Cl |
| InChIKey | WEAJZXNPAWBCOA-INIZCTEOSA-N |
Chemical Property Profile of Avanafil
Property Insights of Avanafil
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Avanafil. The TPSA of 125.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Avanafil. Following Lipinski's Rule of Five, Avanafil has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Avanafil?
The CAS number of Avanafil is 647841-09-6.
What is the molecular formula of Avanafil?
The molecular formula of Avanafil is C23H26ClN7O3.
What is the molecular weight of Avanafil?
The molecular weight of Avanafil is 483.17856 g/mol.
Where can I buy Avanafil?
You can request a quote for Avanafil directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Avanafil?
Yes, CoreyChem provides custom synthesis services for Avanafil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.