![N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine structure](/static/products/838/83890-30-6.webp)
N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine
TL;DR: N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine (CAS 83890-30-6) is a chemical compound with molecular formula C10H8ClF3N2S and molecular weight 280.00488 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine
Also Known As: N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine, N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiaz
Technical Specifications
| Molecular Formula | C10H8ClF3N2S |
| Molecular Weight | 280.00488 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 49.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 280.00488 Da |
| Heavy Atoms | 17 |
| Complexity | 308.0 |
| SMILES | C1CSC(=N1)NC2=C(C=CC(=C2)C(F)(F)F)Cl |
| InChIKey | MHJKUGMXMXGUNB-UHFFFAOYSA-N |
Chemical Property Profile of N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine
Property Insights of N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine
The XLogP value of 3.2 indicates that N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.7 Ų, N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine?
The CAS number of N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine is 83890-30-6.
What is the molecular formula of N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine?
The molecular formula of N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine is C10H8ClF3N2S.
What is the molecular weight of N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine?
The molecular weight of N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine is 280.00488 g/mol.
Where can I buy N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine?
You can request a quote for N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine?
Yes, CoreyChem provides custom synthesis services for N-[2-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.