![1-[3-(Trifluoromethoxy)benzyl]piperazine structure](/static/products/868/868054-25-5.webp)
1-[3-(Trifluoromethoxy)benzyl]piperazine
TL;DR: 1-[3-(Trifluoromethoxy)benzyl]piperazine (CAS 868054-25-5) is a chemical compound with molecular formula C12H15F3N2O and molecular weight 260.11365 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[[3-(trifluoromethoxy)phenyl]methyl]piperazine
Also Known As: 1-[3-(Trifluoromethoxy)benzyl]piperazine, 1-{[3-(trifluoromethoxy)phenyl]methyl}piperazine, 1-[[3-(trifluoromethoxy)phenyl]methyl]piperazine, 1-(3-(Trifluoromethoxy)benzyl)piperazine, 1-3-(Trifluoromethoxy)BenzylPiperazine
Technical Specifications
| Molecular Formula | C12H15F3N2O |
| Molecular Weight | 260.11365 g/mol |
| XLogP | 2.3 |
| Topological Polar Surface Area (TPSA) | 24.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 260.11365 Da |
| Heavy Atoms | 18 |
| Complexity | 254.0 |
| SMILES | C1CN(CCN1)CC2=CC(=CC=C2)OC(F)(F)F |
| InChIKey | GOLWWZWJWXGGPC-UHFFFAOYSA-N |
Chemical Property Profile of 1-[3-(Trifluoromethoxy)benzyl]piperazine
Property Insights of 1-[3-(Trifluoromethoxy)benzyl]piperazine
The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-[3-(Trifluoromethoxy)benzyl]piperazine. With a topological polar surface area (TPSA) of 24.5 Ų, 1-[3-(Trifluoromethoxy)benzyl]piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[3-(Trifluoromethoxy)benzyl]piperazine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-[3-(Trifluoromethoxy)benzyl]piperazine?
The CAS number of 1-[3-(Trifluoromethoxy)benzyl]piperazine is 868054-25-5.
What is the molecular formula of 1-[3-(Trifluoromethoxy)benzyl]piperazine?
The molecular formula of 1-[3-(Trifluoromethoxy)benzyl]piperazine is C12H15F3N2O.
What is the molecular weight of 1-[3-(Trifluoromethoxy)benzyl]piperazine?
The molecular weight of 1-[3-(Trifluoromethoxy)benzyl]piperazine is 260.11365 g/mol.
Where can I buy 1-[3-(Trifluoromethoxy)benzyl]piperazine?
You can request a quote for 1-[3-(Trifluoromethoxy)benzyl]piperazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-[3-(Trifluoromethoxy)benzyl]piperazine?
Yes, CoreyChem provides custom synthesis services for 1-[3-(Trifluoromethoxy)benzyl]piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.